Friday, 19 September 2014

Ebola Virus – Is truth stranger than fiction?

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What is Ebola?

Ebola is a virus and like other viral illnesses, causes fever, body aches, headache and sore throat.  Unlike most viruses, it can also cause internal bleeding, causing it to also be known as “hemorrhagic fever.”  It is native to Africa, and was first found along the Ebola River.  It is thought to live in animals such as monkeys, bats or rodents, but exactly where is unknown.  It can spread to humans from contact with an infected animal, and is spread from infected person to another by contact with body fluids – blood or other droplets.  It is not an airborne virus like the flu.  
Symptoms can be seen from 2-21 days after exposure to infected fluids.  Ebola has a 40-90% fatality rate - which is why it evokes such fear and makes for thrilling subject matter in books and movies.  Outbreaks are usually limited by isolating the sick and preventing further spread of the virus – since humans are not the natural host, the outbreak burns out.

What is happening in Africa?

There have been sporadic outbreaks of Ebola in Africa since we began tracking such things.  The last was 2 years ago in Uganda and The Democratic Republic of the Congo.  Both outbreaks involved less than 100 people.  This pattern has been seen over the past 10 years.  This map shows all cases since 1976 – both locations and number of cases.
In March 2014, the first West African cases were reported, and as of the end of July, over 1300 cases and 700 deaths have been reported in Guinea, Sierra Leone, Liberia and Nigeria.  This outbreak is far larger than the usual outbreaks; in fact this epidemic has more cases than the last 10 years combined.  Why this outbreak is larger and growing is not clear.  Analysis of the current Ebola Virus shows it to be a common form of the virus, not a “superbug” or mutant strain, which would mean that the population is either more susceptible or not able to isolate patients safely to avoid coming into contact with infected secretions.

Treatment

Ebola is a virus, and there is no specific treatment proven to kill the virus.  So, we treat it like we do a cold – support the patient with fluids and nutrition, and hope their immune system will defeat the virus.  There are experimental treatments that have been shown effective in animals, but no human trials have been performed as yet.  Doctors and hospitals have been receiving alerts from the CDC to increase awareness so doctors encountering people traveling from West Africa with fever are evaluated for possible Ebola, and to implement appropriate infection control procedures – just like we do for other contagious diseases.  The patient transported to Emory will be placed in an isolation room and treated by those who train to handle infectious material, limiting the chance of spread of Ebola to the US population.

What does this mean for us?

The average person should not be concerned with catching Ebola, even if you are in the vicinity of Emory Hospital.  Ebola is not an airborne virus – meaning you need to have direct contact with infected droplets to be infected.  You can not catch Ebola by breathing the same air as someone who has Ebola.  In addition, the plane the patient travelled on was not a commercial flight and was set up to prevent the spread of droplets.  Same for the ambulance that took the patient to the hospital.  So I do not think there is a high contagion risk in the US.  The CDC has issued a travel advisory, recommending non-essential travelers leave the affected areas in West Africa, and for those in the US to avoid travel there.  They are also implementing screening and reporting systems to identify and isolate potentially sick people boarding planes from the area, as well as decontamination procedures for the airlines, as they have done with other infections like SARS.  So as frightening as Ebola is, and no matter what happened in that movie you saw, there is little risk of infection to the average person.

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